Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529435 | 0.80 | CYP11B1 (0.49) | RAB9ANPC1TDP1SMN1; SMN2CASP3 | |
| SCHEMBL28532686 | 0.78 | HDAC1 (0.48) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL28547187 | 0.74 | CA1 (0.45) | RAB9ANPC1SMN1; SMN2NOTUMTSHR | |
| SCHEMBL23176766 | 0.72 | RAB9A (0.59) | RAB9ANPC1TDP1SMN1; SMN2CASP3 | |
| SCHEMBL31432693 | 0.71 | NOTUM (0.40) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL28543271 | 0.70 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2NOTUMIKBKB | |
| SCHEMBL28540545 | 0.70 | NPC1 (0.44) | RAB9ANPC1NOTUMIKBKBTSHR | |
| SCHEMBL29183379 | 0.69 | RAB9A (0.50) | RAB9ANPC1TDP1SMN1; SMN2CASP3 | |
| SCHEMBL4879849 | 0.67 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2CASP3SENP8 | |
| SCHEMBL28532802 | 0.67 | CYP11B1 (0.48) | RAB9ANPC1SMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538058-B | Preparation method of oxazole-containing cyclic sulfone compound | 温州大学新材料与产业技术研究院 | 2022-05-27 | — | — | CN | disclosed |
| CN-112538058-A | Preparation method of oxazole-containing cyclic sulfone compound | 温州大学新材料与产业技术研究院 | 2021-03-23 | — | — | CN | disclosed |