Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.66 |
| ▸ | NPC1 | O15118 | 11/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471533 | 0.87 | RAB9A (0.77) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL29231867 | 0.86 | TSHR (0.62) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL12794313 | 0.86 | RAB9A (0.66) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL12776790 | 0.84 | RAB9A (0.52) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL365956 | 0.84 | ALOX15 (0.65) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL3295181 | 0.84 | RAB9A (0.72) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL28743529 | 0.83 | TSHR (0.62) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL272773 | 0.81 | RAB9A (0.73) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL4342614 | 0.80 | ALOX15 (0.69) | RAB9ANPC1ATMTSHRALOX15 | |
| SCHEMBL10495074 | 0.79 | RAB9A (0.66) | RAB9ANPC1ATMTSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | claimed |
| CN-109705012-B | Preparation method of 2, 5-diaryl five-membered heterocyclic aromatic hydrocarbon | 西北师范大学 | 2022-04-05 | — | — | CN | disclosed |
| US-20100013386-A1 | NEAR INFRARED EMITTING ORGANIC COMPOUNDS AND ORGANIC DEVICES USING THE SAME | THOMPSON MARK E | 2010-01-21 | — | — | US | disclosed |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | RAB9A 3960/4885NPC1 2981/4885ATM 3878/4885 |
| US-20100013386-A1 | NEAR INFRARED EMITTING ORGANIC COMPOUNDS AND ORGANIC DEVICES USING THE SAME | PPOX, PPIL1, PPIF | RAB9A 4468/4885NPC1 2012/4885ATM 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.