Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 8/20 | 0.35 |
| ▸ | VHL | P40337 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987782 | 0.81 | PARG (0.35) | PARGVHLEPHX2MEN1KMT2A | |
| SCHEMBL28540594 | 0.81 | PARG (0.35) | PARGVHLEPHX2MEN1KMT2A | |
| SCHEMBL1320181 | 0.78 | VHL (0.41) | PARGVHLEPHX2MEN1KMT2A | |
| SCHEMBL18256182 | 0.78 | PARG (0.35) | PARGVHLEPHX2MEN1KMT2A | |
| SCHEMBL1320408 | 0.75 | VHL (0.41) | PARGVHLEPHX2MEN1KMT2A | |
| SCHEMBL18256114 | 0.75 | VHL (0.39) | PARGVHLEPHX2MEN1KMT2A | |
| SCHEMBL18256181 | 0.69 | VHL (0.38) | PARGVHLEPHX2MEN1KMT2A | |
| SCHEMBL23152007 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL1320569 | 0.67 | S1PR1 (0.40) | VHLEPHX2MEN1KMT2ACHRNB2 | |
| SCHEMBL15687144 | 0.65 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709323-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-11-20 | — | — | CN | disclosed |