SCHEMBL23152007

SCHEMBL23152007

COS(=O)(=O)CC1CCC1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15687144 0.95 ALDH1A1 (0.34) ALDH1A1
SCHEMBL8538497 0.93 ALDH1A1 (0.37) ALDH1A1
SCHEMBL11606604 0.90
SCHEMBL28645664 0.80 MAOA (0.37)
SCHEMBL21410746 0.80 TDP1 (0.36)
SCHEMBL28359345 0.80 MAOA (0.37)
SCHEMBL28924607 0.80
SCHEMBL4437441 0.80 CNR2 (0.33)
SCHEMBL14898460 0.79
SCHEMBL28381486 0.79 NCF1 (0.43) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111108105-B Heterocyclic compounds as PAD inhibitors 朱比兰特埃皮帕德有限公司 2023-03-31 CN disclosed
WO-2021057190-A1 QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF 上海阳帆医药科技有限公司 2021-04-01 WO disclosed
CN-111108105-A Heterocyclic compounds as PAD inhibitors 朱比兰特埃皮帕德有限公司 2020-05-05 CN disclosed
CN-101857549-B Synthetic method of (1S)-4,5-dimethoxy-1-(aminomethyl)benzocyclobutane ZHEJIANG MENOVO PHARMACEUTICAL CO LTD 2013-04-10 CN disclosed
CN-101857549-A Synthetic method of (1S)-4,5-Dimethoxy-1-(aminomethyl)benzocyclobutane ZHEJIANG MENOVO PHARMACEUTICAL CO LTD 2010-10-13 CN disclosed