Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.84 |
| ▸ | CCR1 | P32246 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SPR | P35270 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.58 |
| ▸ | EED | O75530 | 1/20 | 0.58 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.58 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.58 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.58 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854347 | 0.95 | HPGD (0.84) | HPGDCCR1MAPTSPRALDH1A1 | |
| SCHEMBL2850603 | 0.94 | HPGD (0.73) | HPGDCCR1MAPTSPRALDH1A1 | |
| SCHEMBL2856089 | 0.91 | HPGD (1.00) | HPGDCCR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2857860 | 0.88 | CCR1 (0.75) | HPGDCCR1MAPTSPRALDH1A1 | |
| SCHEMBL2850617 | 0.88 | HPGD (0.84) | HPGDCCR1ALDH1A1NPC1RAB9A | |
| SCHEMBL2855676 | 0.86 | CCR1 (0.63) | HPGDCCR1MAPTSPRNPC1 | |
| SCHEMBL2852102 | 0.84 | ALDH1A1 (0.67) | HPGDCCR1MAPTALDH1A1NPC1 | |
| SCHEMBL2852886 | 0.84 | CCR1 (0.62) | HPGDCCR1MAPTALDH1A1NPC1 | |
| SCHEMBL2854454 | 0.83 | HPGD (0.72) | HPGDCCR1MAPTALDH1A1NPC1 | |
| SCHEMBL2856450 | 0.83 | HPGD (0.74) | HPGDCCR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |