Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EED | O75530 | 1/20 | 0.51 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.51 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.51 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.51 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854454 | 0.93 | HPGD (0.72) | CCR1HPGDNPC1RAB9APOLB | |
| SCHEMBL2859795 | 0.89 | NPC1 (0.59) | CCR1HPGDNPC1RAB9APOLB | |
| SCHEMBL2852637 | 0.89 | NR3C1 (0.64) | CCR1HPGDNPC1RAB9ANPSR1 | |
| SCHEMBL2854347 | 0.86 | HPGD (0.84) | CCR1HPGDNPC1RAB9ANPSR1 | |
| SCHEMBL2850603 | 0.84 | HPGD (0.73) | CCR1HPGDNPC1RAB9ANPSR1 | |
| SCHEMBL2850363 | 0.84 | CCR1 (0.59) | CCR1HPGDPOLBALDH1A1LMNA | |
| SCHEMBL2854061 | 0.84 | HPGD (0.84) | CCR1HPGDNPC1RAB9ANPSR1 | |
| SCHEMBL2854625 | 0.81 | POLB (0.48) | CCR1HPGDNPC1RAB9APOLB | |
| SCHEMBL2857860 | 0.80 | CCR1 (0.75) | CCR1HPGDNPSR1ALDH1A1MAPT | |
| SCHEMBL2854397 | 0.79 | HPGD (0.72) | CCR1HPGDNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |