SCHEMBL28540865

SCHEMBL28540865

BOP(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ESR1 P03372 4/20 0.36
ESR2 Q92731 4/20 0.36
LTA4H P09960 1/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.32
DPP4 P27487 2/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21111873 0.85 ACHE (0.43) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL21111849 0.82 ACHE (0.44) CYP3A4TDP1TSHRGAAALDH1A1
SCHEMBL21111833 0.82 CA4 (0.52) TDP1LTA4HKDM4EALDH1A1CA4
SCHEMBL21111822 0.80 CYP2A6 (0.40) CYP3A4TDP1KDM4EALDH1A1
SCHEMBL21111845 0.80 TSHR (0.35) CYP3A4TDP1TSHR
SCHEMBL187947 0.79 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2LTA4H
SCHEMBL21111817 0.78 CA1 (0.44) TDP1TSHRALDH1A1CA4
SCHEMBL21111884 0.78 CA4 (0.43) CYP3A4LTA4HTSHRKDM4EALDH1A1
SCHEMBL757106 0.78 TDP1 (0.50) CYP3A4TDP1ESR1ESR2LTA4H
SCHEMBL21111750 0.77 ALDH1A1 (0.34) CYP3A4TDP1TSHRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109503639-B Synthesis method of trans-2-substituted cycloalkyl potassium trifluoroborate 沧州普瑞东方科技有限公司 2021-04-16 CN claimed
CN-109503639-B Synthesis method of trans-2-substituted cycloalkyl potassium trifluoroborate 沧州普瑞东方科技有限公司 2021-04-16 CN disclosed