Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.30 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.30 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.30 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL3721718 | 0.91 | ALDH1A1 (0.50) | TDP1CYP3A4KDM4EGAAESR1 | |
| SCHEMBL28540865 | 0.78 | CYP3A4 (0.47) | TDP1CYP3A4KDM4EGAAESR1 | |
| SCHEMBL14612054 | 0.75 | CYP3A4 (0.45) | TDP1CYP3A4KDM4EGAAESR1 | |
| SCHEMBL187947 | 0.75 | CYP3A4 (0.45) | TDP1CYP3A4KDM4EESR1ESR2 | |
| SCHEMBL8463498 | 0.75 | CYP3A4 (0.45) | TDP1CYP3A4KDM4EGAAESR1 | |
| SCHEMBL11141481 | 0.73 | CYP3A4 (0.43) | TDP1CYP3A4KDM4EGAAESR1 | |
| SCHEMBL195629 | 0.73 | LTA4H (0.43) | TDP1CYP3A4ESR1ESR2TSHR | |
| SCHEMBL16050052 | 0.73 | CYP3A4 (0.43) | TDP1CYP3A4KDM4EGAAESR1 | |
| SCHEMBL17189423 | 0.73 | CYP3A4 (0.43) | TDP1CYP3A4KDM4EGAAESR1 | |
| Hydrochloric Acid SCHEMBL28963009 | 0.73 | CYP3A4 (0.43) | TDP1CYP3A4KDM4EESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192275-A | Cyclobutadiene-containing luminescent material, preparation method and application | 深圳大学 | 2025-06-24 | — | — | CN | claimed |
| CN-118307475-A | Preparation method of stable isotope labeled fluxapyroxad internal standard reagent | 谱同生物医药科技(常州)有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-118090990-A | Preparation method of stable isotope labeled hypnone internal standard reagent | 谱同生物医药科技(常州)有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-118063383-A | Rhodium-catalyzed coupling method of cycloheptatriene and aromatic amine | 中国科学院大连化学物理研究所 | 2024-05-24 | — | — | CN | claimed |
| CN-112679539-B | Compound containing bis-diphenyl phosphinic oxygen structure and preparation method thereof | 李萍萍 | 2024-02-13 | — | — | CN | claimed |
| CN-115960051-B | Preparation method of stable isotope labeled pyrimethanil internal standard reagent | 谱同生物医药科技(常州)有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-114591128-B | Direct cross-coupling method of aryl sulfide salt and aryl bromide | 南京工业大学 | 2023-08-22 | — | — | CN | claimed |
| CN-108250180-B | Organic compound, and organic light emitting diode and organic light emitting display device including the same | 乐金显示有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-114854005-B | Method for synthesizing polyamide by olefin hydroamine carbonylation | 中国科学技术大学 | 2023-03-10 | — | — | CN | claimed |
| CN-113801015-B | Method for synthesizing aromatic carboxylic acid compound by using carbon dioxide | 华南理工大学 | 2022-11-18 | — | — | CN | claimed |
| CN-111039773-B | Method for synthesizing alpha-acrylic acid compound by catalyzing carbon dioxide and alkyne with palladium | 华南理工大学 | 2021-09-21 | — | — | CN | claimed |
| CN-109796297-B | 1, 3-conjugated diene compound, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2021-09-03 | — | — | CN | claimed |
| CN-112679539-A | Compound containing bis (diphenylphosphine oxide) structure and preparation method thereof | 李萍萍 | 2021-04-20 | — | — | CN | claimed |
| CN-112457344-A | Synthesis method of p-xylyl bis (diphenylphosphine) oxide | 南京正荣医药化学有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-111303162-B | Preparation method of 2-chloro-7-cyclopentyl-7H-pyrrolo [2,3-d ] pyrimidine-6-carboxylic acid | 天津法莫西医药科技有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-103570761-B | A kind of copper complex/composite luminescent material to oxygen sensitive and preparation method thereof and the application on oxygen sensor device | BOHAI UNIVERSITY (CN) | 2016-05-25 | — | — | CN | claimed |
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PHOSPHOENIX SARL (FR) | 2010-04-22 | — | — | US | claimed |
| EP-1205486-B1 | Improved method for the preparation of enantiomerically pure (5,5'-dichloro-6,6'-dimethoxybiphenyl-2,2'-diyl)-bis-(diphenylphosphine oxides) | BAYER CHEMICALS AG (DE) | 2004-02-11 | — | — | EP | claimed |
| US-6489513-B2 | REACTING AROMATIC BROMINE COMPOUND WITH DIPHENYLPHOSPHINIC CHLORIDE IN A MIXTURE OF TETRAHYDROFURAN AND AROMATIC HYDROCARBON TO GIVE A DIPHENYLPHOSPHINE OXIDE, ISOLATING, METALATING; REACTING WITH IODINE, REACTING WITH COPPER | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-03 | — | — | US | claimed |
| US-20020058814-A1 | Process for the preparation of enantiomerically pure (5,5'-dichloro-6,6'-dimethoxy-biphenyl-2,2'-diyl)- bis(diphenylphosphine oxides) | LANXESS DEUTSCHLAND GMBH (DE) | 2002-05-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099875-A1 | NEW ORTHO-FUNCTIONALIZED P-CHIRAL ARYLPHOSPHINES AND DERIVATIVES: THEIR PREPARATION AND USE IN ASYMMETRIC CATALYSIS | PNP, NANP, PHOSPHO1 | TDP1 3756/4885CYP3A4 849/4885KDM4E 2286/4885 |
| US-20020058814-A1 | Process for the preparation of enantiomerically pure (5,5'-dichloro-6,6'-dimethoxy-biphenyl-2,2'-diyl)- bis(diphenylphosphine oxides) | DDT, HDHD5, DDC | TDP1 3405/4885CYP3A4 150/4885KDM4E 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.