Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23357726 | 0.86 | ROCK2 (0.37) | S1PR1S1PR5SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL19208899 | 0.83 | ROCK2 (0.38) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29391022 | 0.83 | S1PR1 (0.36) | S1PR1S1PR5SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL197441 | 0.83 | S1PR1 (0.36) | S1PR1S1PR5SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL29350531 | 0.83 | S1PR1 (0.36) | S1PR1S1PR5SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL21331777 | 0.79 | SMN1; SMN2 (0.43) | S1PR1NPC1RAB9AGALR1HTR2A | |
| SCHEMBL28979133 | 0.79 | HDAC1 (0.40) | S1PR1S1PR5SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL21331779 | 0.79 | HTR6 (0.39) | ROCK2 | |
| SCHEMBL3929841 | 0.79 | SIGMAR1 (0.35) | S1PR1S1PR5SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL29584884 | 0.79 | SIGMAR1 (0.35) | S1PR1S1PR5SIGMAR1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240616-B | Tribiaryl monophosphine ligands, methods for their preparation and use in catalytic coupling reactions | 东莞市均成高新材料有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-110240616-B | Tribiaryl monophosphine ligands, methods for their preparation and use in catalytic coupling reactions | 东莞市均成高新材料有限公司 | 2021-03-23 | — | — | CN | disclosed |