Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17041577 | 0.88 | MAOB (0.52) | KDM1AMAOAMAOBNPC1LMNA | |
| SCHEMBL4046366 | 0.85 | THRA (0.48) | KDM1ACTSVCTSLFOLH1MEN1 | |
| SCHEMBL25365036 | 0.82 | CTSV (0.52) | CTSVCTSLFOLH1MEN1KMT2A | |
| SCHEMBL14882664 | 0.82 | CTSV (0.52) | KDM1ACTSVCTSLFOLH1MEN1 | |
| SCHEMBL4153049 | 0.81 | NPC1 (0.55) | KDM1AMAOAMAOBCTSVCTSL | |
| SCHEMBL9321792 | 0.81 | MEN1 (0.52) | MAOBMEN1KMT2ALMNAHPGD | |
| SCHEMBL27901340 | 0.80 | KDM1A (0.59) | KDM1AMAOAMAOBLMNAHPGD | |
| SCHEMBL15969027 | 0.80 | MEN1 (0.63) | MEN1KMT2APTGER1MRGPRX4LMNA | |
| SCHEMBL24379393 | 0.79 | CTSV (0.50) | CTSVCTSLFOLH1MEN1KMT2A | |
| SCHEMBL28551712 | 0.79 | FOLH1 (0.54) | KDM1ACTSVCTSLFOLH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995567-B | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2022-11-25 | — | — | CN | disclosed |
| CN-111995567-A | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2020-11-27 | — | — | CN | disclosed |