SCHEMBL4153049

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15716510	0.88	ALDH1A1 (0.58)	ALDH1A1PTGER1CTSVCTSLNR4A2
	SCHEMBL4143247	0.88	NPC1 (0.52)	NPC1MRGPRX4KDM1AMAOAMAOB
	SCHEMBL4145578	0.86	ALDH1A1 (0.58)	NPC1MRGPRX4KDM1AALDH1A1MAOA
	SCHEMBL5313068	0.85	NPC1 (0.50)	NPC1MRGPRX4KDM1AALDH1A1MAOA
	SCHEMBL3424839	0.83	ALDH1A1 (0.55)	ALDH1A1MAOBPTGER1NR4A2NR4A1
	SCHEMBL27982373	0.83	BRD4 (0.49)	NPC1MRGPRX4KDM1AALDH1A1MAOA
	SCHEMBL26942219	0.82	KDM1A (0.61)	NPC1MRGPRX4KDM1AMAOAMAOB
	SCHEMBL1305739	0.82	PTGER1 (0.61)	NPC1ALDH1A1PTGER1CTSVCTSL
	SCHEMBL8673772	0.82	TDP1 (0.54)	ALDH1A1MAOBPTGER1CTSVCTSL
	SCHEMBL5307002	0.82	NPC1 (0.47)	NPC1MRGPRX4KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.