Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK12 | Q9NYV4 | 7/20 | 0.49 |
| ▸ | IDH1 | O75874 | 2/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CCNK | O75909 | 6/20 | 0.45 |
| ▸ | IDH2 | P48735 | 1/20 | 0.44 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292416 | 1.00 | CDK12 (0.49) | CDK12IDH1USP30MAPK3HDAC4 | |
| SCHEMBL22895585 | 1.00 | CDK12 (0.49) | CDK12IDH1USP30MAPK3HDAC4 | |
| SCHEMBL22895533 | 0.88 | USP30 (0.52) | CDK12IDH1USP30CCNKCDK13 | |
| SCHEMBL23292274 | 0.88 | USP30 (0.52) | CDK12IDH1USP30CCNKCDK13 | |
| SCHEMBL28552023 | 0.88 | USP30 (0.52) | CDK12IDH1USP30CCNKCDK13 | |
| SCHEMBL28544916 | 0.87 | CDK12 (0.56) | CDK12IDH1USP30CCNKCDK13 | |
| SCHEMBL23292333 | 0.87 | CDK12 (0.56) | CDK12IDH1USP30CCNKCDK13 | |
| SCHEMBL22895770 | 0.87 | CDK12 (0.56) | CDK12IDH1USP30CCNKCDK13 | |
| SCHEMBL23292227 | 0.87 | CDK12 (0.65) | CDK12IDH1USP30MAPK3HDAC4 | |
| SCHEMBL22895468 | 0.87 | CDK12 (0.65) | CDK12IDH1USP30MAPK3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638373-A | Cyclin-dependent kinase inhibitors | 金耐特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |