Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13290860 | 0.75 | MAPK1 (0.62) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL27974930 | 0.74 | METAP2 (0.76) | KMT2AMEN1CA1CA2CA9 | |
| SCHEMBL3503756 | 0.73 | ALDH1A1 (0.50) | KMT2AMEN1HTTKDM4EMAPT | |
| SCHEMBL51046 | 0.73 | MAPK1 (0.68) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL29663898 | 0.73 | MAPK1 (0.68) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL7180056 | 0.71 | MAPK1 (0.70) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL27592567 | 0.71 | MAPK1 (0.70) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL4617096 | 0.70 | MAPK1 (0.68) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL863061 | 0.70 | MAPK1 (0.68) | KMT2AMEN1MAPK1CA1CA2 | |
| SCHEMBL11679037 | 0.70 | MAPK1 (0.68) | KMT2AMEN1MAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109771425-B | Quinoline-containing small molecule inhibitor and application thereof in inhibition of Ornithine Decarboxylase (ODC) | 湖北工业大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-109771425-B | Quinoline-containing small molecule inhibitor and application thereof in inhibition of Ornithine Decarboxylase (ODC) | 湖北工业大学 | 2021-04-06 | — | — | CN | disclosed |