Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663898 | 1.00 | MAPK1 (0.68) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL8703196 | 0.92 | MAPK1 (0.58) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL6894312 | 0.85 | GLO1 (0.61) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL28490306 | 0.85 | GAA (0.51) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL8734368 | 0.85 | ALDH1A1 (0.55) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL28476864 | 0.84 | MAPK1 (0.54) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL27592567 | 0.82 | MAPK1 (0.70) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL7180056 | 0.82 | MAPK1 (0.70) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL8590457 | 0.82 | MAPK1 (0.48) | MAPK1CA1CA2CA9KDM4E | |
| SCHEMBL50688 | 0.81 | MAPK1 (1.00) | MAPK1CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040443-A | Preparation of cinchona alkaloid-metal complex and application of cinchona alkaloid-metal complex in asymmetric cyanidation | 哈尔滨理工大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119081574-A | Flame-retardant PET (polyethylene terephthalate) adhesive tape and preparation method thereof | 常州市白鹭电器有限公司 | 2024-12-06 | — | — | CN | claimed |
| CN-115304543-B | Preparation method and product of aryl sulfonamide containing norbornenyl and application of aryl sulfonamide | 南京林业大学 | 2024-08-20 | — | — | CN | claimed |
| CN-117205211-B | Application of quinoline compound in preparation of fish parasitic protozoan resisting medicine | 西北农林科技大学深圳研究院 | 2024-04-05 | — | — | CN | claimed |
| CN-117205211-A | Application of quinoline compound in preparation of fish parasitic protozoan resisting medicine | 西北农林科技大学深圳研究院 | 2023-12-12 | — | — | CN | claimed |
| CN-115304543-A | Preparation method of aryl sulfonamide containing norbornenyl, product and application thereof | 南京林业大学 | 2022-11-08 | — | — | CN | claimed |
| WO-2013102936-A1 | N-(3-((DIETHYLAMINO) METHYL)-4-HYDROXYPHENYL)-N-(QUINOLIN-4-YL) SULFONAMIDES FOR THE TREATMENT OF TUBERCULOSIS AND PROCESS OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-07-11 | — | — | WO | claimed |
| EP-1754705-A2 | Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders | Genentech, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-4414275-A | ETCHING, POLYVINYL FORMAL, PHOTOPOLYMERIZABLE ACRYLATE, RELEASE COATING | LOCTITE (IRELAND) LIMITED (IE) | 1983-11-08 | — | — | US | claimed |
| US-3959100-A | OPACIFIER | SCM CORPORATION (US) | 1976-05-25 | — | — | US | claimed |
| US-20260146025-A1 | CRYSTALLINE POLYMORPHS OF MITAPIVAT AND MITAPIVAT HEMISULFATE | TIANISH LABORATORIES PRIVATE LIMITED (IN) | 2026-05-28 | — | — | US | disclosed |
| CN-122079862-A | Natural product 3-methyl carbazole derivative and preparation method and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-121202849-B | Coumarin-pyrazole ring hybridization derivative and preparation method and application thereof | NORTHWEST UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-12612381-B2 | Crystalline forms of n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide | AGIOS PHARMACEUTICALS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-4083404-A | Oil recovery process utilizing air and superheated steam | TEXACO INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4061639-A | MICROBIOCIDES | THE DOW CHEMICAL COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4048078-A | Oil recovery process utilizing air and superheated steam | TEXACO INC. (US) | 1977-09-13 | — | — | US | disclosed |
| US-4043922-A | Secondary oil recovery process using oxyalkylated additives | TEXACO INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612381-B2 | Crystalline forms of n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide | PKLR, PKM, HBZ | MAPK1 2208/4885CA1 4824/4885CA2 2650/4885 |
| US-20260146025-A1 | CRYSTALLINE POLYMORPHS OF MITAPIVAT AND MITAPIVAT HEMISULFATE | PKM, HBZ, PRKCZ | MAPK1 1543/4885CA1 4555/4885CA2 734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.