Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 6/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20445970 | 1.00 | BTK (0.43) | BTKRIPK1HRH3ACACBLRRK2 | |
| SCHEMBL28544434 | 0.82 | BTK (0.41) | BTKRIPK1HRH3ACACBLRRK2 | |
| SCHEMBL28536890 | 0.78 | HRH3 (0.43) | HRH3ACACB | |
| SCHEMBL20507833 | 0.78 | HRH3 (0.43) | HRH3ACACB | |
| SCHEMBL29283185 | 0.77 | LMNA (0.41) | HRH3LOXL2GPR119 | |
| SCHEMBL16684935 | 0.77 | HRH3 (0.40) | HRH3GPR119 | |
| SCHEMBL20445920 | 0.76 | HRH3 (0.37) | HRH3ACACBGPR119 | |
| SCHEMBL28542435 | 0.75 | HRH3 (0.55) | BTKHRH3ACACB | |
| SCHEMBL17077859 | 0.75 | CYP2C19 (0.53) | RIPK1HRH3ACACB | |
| SCHEMBL28913940 | 0.75 | HRH3 (0.56) | HRH3DPP4DPP9GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-B | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2021-04-06 | — | — | CN | disclosed |