Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.38 |
| ▸ | DCK | P27707 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639677 | 0.84 | LMNA (0.42) | LMNAHRH3GPR119 | |
| SCHEMBL16684935 | 0.84 | HRH3 (0.40) | HRH3GPR119 | |
| SCHEMBL12288882 | 0.82 | CYP3A4 (0.51) | LMNALOXL2 | |
| SCHEMBL17077859 | 0.82 | CYP2C19 (0.53) | HRH3DCK | |
| SCHEMBL17748977 | 0.81 | LMNA (0.39) | LMNAGPR119LOXL2KMO | |
| SCHEMBL1775467 | 0.80 | LMNA (0.64) | LMNA | |
| SCHEMBL28382199 | 0.78 | JAK2 (0.45) | HRH3DCKLOXL2 | |
| SCHEMBL20445970 | 0.77 | BTK (0.43) | HRH3GPR119LOXL2 | |
| SCHEMBL28541728 | 0.77 | BTK (0.43) | HRH3GPR119LOXL2 | |
| SCHEMBL25197786 | 0.77 | LMNA (0.58) | LMNALOXL2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084865-A | Pyrimidine compound containing aminopiperidine structure, and preparation method and application thereof | 贵州大学 | 2024-05-28 | — | — | CN | disclosed |