Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195571 | 0.76 | TDP1 (0.36) | TDP1HPGDHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL9476067 | 0.67 | LMNA (0.50) | HPGDALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL6907405 | 0.66 | KMT2A (0.38) | TDP1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8441293 | 0.66 | KMT2A (0.49) | TDP1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL7660067 | 0.65 | LMNA (0.37) | TDP1HPGDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9494256 | 0.65 | PPARG (0.38) | TDP1 | |
| SCHEMBL9492617 | 0.65 | KMT2A (0.40) | TDP1HPGDLMNAMEN1KMT2A | |
| SCHEMBL9542985 | 0.64 | DPP4 (0.42) | TDP1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| Cafenstrole SCHEMBL54625 | 0.64 | KMT2A (0.49) | TDP1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL204666 | 0.64 | DPP4 (0.34) | TDP1ALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137160-B1 | 4-(4-TRIFLUOROMETHYL-3-THIOBENZOYL)PYRAZOLES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-10-27 | — | — | EP | disclosed |