SCHEMBL9494256

SCHEMBL9494256

CCN(CC)C(=O)n1cnc(S(=O)(=O)Oc2ccc(C)cc2)n1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.38
TRPM8 Q7Z2W7 13/20 0.38
TDP1 Q9NUW8 1/20 0.37
ENPP1 P22413 1/20 0.35
DPP4 P27487 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9495195 0.90 KMT2A (0.40) TRPM8DPP4
SCHEMBL9494430 0.89 YAP1 (0.40) TRPM8DPP4
SCHEMBL9492475 0.89 MGLL (0.42) TRPM8DPP4
SCHEMBL9491411 0.87 ALDH1A1 (0.35) DPP4
SCHEMBL9492617 0.86 KMT2A (0.40) TRPM8TDP1
SCHEMBL9504915 0.81 CCNC (0.40) TRPM8
SCHEMBL9493429 0.79 DPP4 (0.38) TDP1DPP4
SCHEMBL9542985 0.77 DPP4 (0.42) TDP1DPP4
SCHEMBL9015551 0.74 DPP4 (0.40) TDP1DPP4
SCHEMBL9544526 0.74 DPP4 (0.40) TDP1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5211739-A Herbicidal-1-(disubstituted carbamoyl or thiocarbamoyl)-1,2,4-triazol-3-yl sulfonates and thisulfonates ROHM AND HAAS COMPANY (US) 1993-05-18 US claimed
JP-5059020-A None JP disclosed
JP-H0559020-A PREPARATION OF SUBSTITUTED PHENOXYSULFONYLCARBAMOYLTRIAZOLE DERIVATIVE MITSUBISHI PETROCHEM CO LTD 1993-03-09 JP disclosed