Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538341 | 0.85 | KMT2A (0.39) | MAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL29113849 | 0.85 | S1PR1 (0.34) | S1PR1S1PR5MAPTALDH1A1MAPK1 | |
| SCHEMBL28536734 | 0.80 | ALDH1A1 (0.36) | PTGS1PTGS2PDCD1CD274MAPT | |
| SCHEMBL28910163 | 0.74 | ALDH1A1 (0.35) | MAPTALDH1A1TDP1 | |
| SCHEMBL28541612 | 0.72 | MEN1 (0.35) | PDCD1CD274MAPTALDH1A1TDP1 | |
| SCHEMBL28542182 | 0.72 | MAOB (0.44) | MAPT | |
| SCHEMBL28969702 | 0.72 | PDK1 (0.40) | ALDH1A1TDP1POLB | |
| SCHEMBL28542266 | 0.71 | HTT (0.33) | PTGS1PTGS2MAPTALDH1A1MAPK1 | |
| SCHEMBL28536735 | 0.71 | ALDH1A1 (0.39) | S1PR1S1PR5PTGS1PTGS2PDCD1 | |
| SCHEMBL28539307 | 0.66 | SNCA (0.38) | MAPTALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574089-A | Photoinduced multifunctional cross-linking agent, and preparation method and application thereof | 中国科学院上海药物研究所 | 2021-03-30 | — | — | CN | disclosed |