Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28546897 | 0.86 | RAB9A (0.43) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL12932912 | 0.78 | NPC1 (0.49) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL21564436 | 0.74 | LATS1 (0.43) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL29890985 | 0.74 | LATS1 (0.43) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL1435912 | 0.73 | NPC1 (0.46) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL21551229 | 0.73 | TSHR (0.48) | RAB9AMAPTTSHRNPC1SMN1; SMN2 | |
| SCHEMBL31407474 | 0.72 | RAB9A (0.45) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL12295518 | 0.72 | RAB9A (0.45) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL28543779 | 0.71 | FDPS (0.45) | RAB9AMAPTTSHRNPC1ATM | |
| SCHEMBL28541779 | 0.70 | HCAR3 (0.46) | RAB9AMAPTTSHRNPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-A | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |