Pyromellitic Acid

Pyromellitic Acid

SCHEMBL28544009

O=C(O)c1cc(C(=O)O)c(C(=O)O)cc1C(=O)O.c1c[nH]cn1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
FKBP5 Q13451 1/20 0.54
KMT2A Q03164 2/20 0.35
NOTUM Q6P988 1/20 0.34
KDM4E B2RXH2 4/20 0.34
MAPT P10636 3/20 0.34
KDM4C Q9H3R0 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 1/20 0.34
KDM6B O15054 1/20 0.34
KDM4A O75164 1/20 0.34
THRB P10828 1/20 0.34
KDM4D Q6B0I6 1/20 0.34
NAPRT Q6XQN6 4/20 0.32
ALOX15 P16050 2/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
BLM P54132 1/20 0.31
AGER Q15109 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL3835971 0.84 KDM4E (0.47) ALDH1A1FKBP5KDM4EMAPTKDM4C
Imidazole SCHEMBL30112751 0.84 KDM4E (0.47) ALDH1A1FKBP5KDM4EMAPTKDM4C
Imidazole SCHEMBL6053658 0.84 KDM4E (0.47) ALDH1A1FKBP5KDM4EMAPTKDM4C
Phthalic Acid SCHEMBL30474600 0.84 ALDH1A1 (0.54) ALDH1A1FKBP5KMT2AKDM4EMAPT
Phthalic Acid SCHEMBL2196833 0.84 ALDH1A1 (0.54) ALDH1A1FKBP5KMT2AKDM4EMAPT
Phthalic Acid SCHEMBL2196835 0.84 ALDH1A1 (0.54) ALDH1A1FKBP5KMT2AKDM4EMAPT
Phthalic Acid SCHEMBL27543991 0.84 ALDH1A1 (0.54) ALDH1A1FKBP5KMT2AKDM4EMAPT
Benzene SCHEMBL28264459 0.83 KDM4E (0.50) ALDH1A1FKBP5KDM4EMAPTKDM4C
Phthalic Acid SCHEMBL11231292 0.82 ALDH1A1 (0.52) ALDH1A1FKBP5KMT2AKDM4EMAPT
Phthalic Acid SCHEMBL27323447 0.82 ALDH1A1 (0.52) ALDH1A1FKBP5KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114551905-A Non-noble metal catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2022-05-27 CN claimed
CN-112691688-A High-activity Co-Ni-Fe Co-embedded non-noble metal catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2021-04-23 CN claimed
CN-114551905-A Non-noble metal catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2022-05-27 CN disclosed