Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858063 | 0.86 | MAPT (0.57) | RAB9ANPC1MAPTNPSR1LMNA | |
| SCHEMBL2880891 | 0.83 | CNR1 (0.54) | RAB9ANPC1MAPTNPSR1LMNA | |
| SCHEMBL2860983 | 0.82 | MAPT (0.49) | RAB9ANPC1MAPTNPSR1LMNA | |
| SCHEMBL2853232 | 0.82 | CCR1 (0.48) | RAB9ANPC1MAPTNPSR1TRPV1 | |
| SCHEMBL2854478 | 0.81 | ITGB3 (0.46) | RAB9ANPC1MAPTNPSR1LMNA | |
| SCHEMBL2854169 | 0.81 | MAPT (0.56) | RAB9ANPC1MAPTNPSR1LMNA | |
| SCHEMBL2862263 | 0.81 | MAPT (0.47) | RAB9ANPC1MAPTNPSR1LMNA | |
| SCHEMBL2880130 | 0.81 | MAPK1 (0.54) | RAB9ANPC1MAPTNPSR1HTT | |
| SCHEMBL2856146 | 0.80 | CNR1 (0.53) | RAB9ANPC1MAPTNPSR1LMNA | |
| SCHEMBL2855981 | 0.80 | MAPT (0.60) | RAB9ANPC1MAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |