Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | NAMPT | P43490 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853232 | 0.91 | CCR1 (0.48) | MAPK1TRPV1MAPTNPC1RAB9A | |
| SCHEMBL2850439 | 0.89 | KMT2A (0.53) | MAPK1NAMPTABCB1NPC1RAB9A | |
| SCHEMBL2858063 | 0.84 | MAPT (0.57) | TRPV1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2880891 | 0.83 | CNR1 (0.54) | HTTMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2857827 | 0.83 | MEN1 (0.55) | MAPK1HTTTRPV1MAPTNPC1 | |
| SCHEMBL2849968 | 0.81 | KMT2A (0.58) | MAPK1HTTTRPV1MAPTRAB9A | |
| SCHEMBL2854401 | 0.81 | RAB9A (0.46) | HTTTRPV1MAPTNPC1RAB9A | |
| SCHEMBL2860283 | 0.81 | KDM4E (0.45) | TRPV1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2856146 | 0.80 | CNR1 (0.53) | MAPK1ABCB1MAPTNPC1RAB9A | |
| SCHEMBL2854322 | 0.80 | ABCB1 (0.45) | MAPK1NAMPTABCB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |