Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880130 | 0.91 | MAPK1 (0.54) | MAPK1MAPTTRPV1NPC1RAB9A | |
| SCHEMBL2850439 | 0.90 | KMT2A (0.53) | MAPK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2856146 | 0.90 | CNR1 (0.53) | MAPK1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2855846 | 0.88 | CNR1 (0.55) | CCR1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2860283 | 0.86 | KDM4E (0.45) | CCR1MAPTALDH1A1TRPV1NPC1 | |
| SCHEMBL2858063 | 0.85 | MAPT (0.57) | CCR1MAPTALDH1A1TRPV1NPC1 | |
| SCHEMBL2854169 | 0.84 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL2880891 | 0.84 | CNR1 (0.54) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2857827 | 0.84 | MEN1 (0.55) | CCR1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL2854345 | 0.84 | MAPT (0.43) | CCR1MAPTALDH1A1TRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |