Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27473771 | 0.91 | ALDH1A1 (0.54) | KMT2APOLBALDH1A1MAPTPARP10 | |
| SCHEMBL29192943 | 0.82 | ALDH1A1 (0.58) | LMNACYP1A2KMT2APOLBALDH1A1 | |
| SCHEMBL6269137 | 0.81 | ALDH1A1 (0.70) | LMNACYP3A4KMT2APOLBALDH1A1 | |
| SCHEMBL6682497 | 0.79 | LMNA (0.55) | LMNACYP1A2CYP3A4MAOAKMT2A | |
| Biphenyl SCHEMBL8014588 | 0.76 | ALDH1A1 (0.63) | LMNACYP3A4KMT2APOLBALDH1A1 | |
| SCHEMBL27525096 | 0.76 | LMNA (0.47) | LMNACYP1A2CYP3A4MAOAKMT2A | |
| SCHEMBL13479832 | 0.76 | KMT2A (0.58) | LMNACYP1A2CYP3A4MAOAKMT2A | |
| SCHEMBL7555577 | 0.76 | ALDH1A1 (0.52) | KMT2APOLBALDH1A1MAPTPARP10 | |
| SCHEMBL42732 | 0.76 | CA1 (0.64) | LMNACYP1A2CYP3A4MAOAKMT2A | |
| SCHEMBL6228872 | 0.75 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112704680-B | Composition for preventing and/or treating organ fibrosis and application and preparation thereof | 广东盛普生命科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-112704680-A | Composition for preventing and/or treating organ fibrosis and application and preparation thereof | 广东盛普生命科技有限公司 | 2021-04-27 | — | — | CN | disclosed |