SCHEMBL28544358

SCHEMBL28544358

OOCCc1ccc(Cl)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.50
HTR3E A5X5Y0 1/20 0.45
HTR3B O95264 1/20 0.45
HTR3A P46098 1/20 0.45
HTR3D Q70Z44 1/20 0.45
HTR3C Q8WXA8 1/20 0.45
IGF1R P08069 1/20 0.44
ALOX15 P16050 1/20 0.44
MAOB P27338 3/20 0.43
IDO1 P14902 6/20 0.43
AGXT P21549 2/20 0.43
GPR84 Q9NQS5 1/20 0.42
AOC3 Q16853 1/20 0.42
MIF P14174 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25810036 0.86 IGF1R (0.50) TAAR1HTR3EHTR3BHTR3AHTR3D
SCHEMBL27564195 0.83 IGF1R (0.52) TAAR1HTR3EHTR3BHTR3AHTR3D
SCHEMBL11228865 0.80 TAAR1 (0.54) TAAR1HTR3EHTR3BHTR3AHTR3D
SCHEMBL28454343 0.76 TAAR1 (0.50) TAAR1IDO1GPR84
SCHEMBL15396308 0.76 CYP1A2 (0.50) TAAR1IGF1RALOX15IDO1AGXT
SCHEMBL357647 0.76 TAAR1 (0.50) TAAR1HTR3EHTR3BHTR3AHTR3D
SCHEMBL28459251 0.76 TAAR1 (0.50) TAAR1MAOBIDO1
SCHEMBL2135113 0.76 TAAR1 (0.68) TAAR1HTR3EHTR3BHTR3AHTR3D
SCHEMBL10587274 0.76 IDO1 (0.48) IDO1
SCHEMBL3169926 0.76 TAAR1 (0.45) TAAR1HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113786834-B Iron (II) -doped bamboo charcoal material and preparation method and application thereof 浙江工业大学 2024-07-19 CN disclosed
CN-110172034-B Preparation method of arylethyl hydrogen peroxide 江苏强盛功能化学股份有限公司 2021-04-02 CN disclosed