Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27564195 | 0.92 | IGF1R (0.52) | IGF1RALOX15SLC6A2HRH1HRH3 | |
| SCHEMBL28544358 | 0.86 | TAAR1 (0.50) | IGF1RALOX15HTR3EHTR3BHTR3A | |
| SCHEMBL9249000 | 0.82 | SLC6A2 (0.64) | IGF1RALOX15SLC6A2HRH1HRH3 | |
| SCHEMBL9672758 | 0.78 | IDO1 (0.63) | IGF1RALOX15SLC6A2HRH1HRH3 | |
| SCHEMBL21700176 | 0.78 | TAAR1 (0.46) | TAAR1SIGMAR1IDO1 | |
| SCHEMBL3655884 | 0.78 | KCNH2 (0.47) | IGF1RALOX15SLC6A2HRH1HRH3 | |
| SCHEMBL10365734 | 0.78 | IGF1R (0.64) | IGF1RALOX15KCNH2HTR3EHTR3B | |
| SCHEMBL18050371 | 0.78 | TAAR1 (0.62) | IGF1RALOX15KCNH2HTR3EHTR3B | |
| SCHEMBL8625873 | 0.77 | IDO1 (0.61) | SLC6A3HTR3ASIGMAR1HDAC3HDAC4 | |
| SCHEMBL28966782 | 0.76 | IGF1R (0.61) | IGF1RALOX15CHRM2KCNH2HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219914-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | Nuray Chemicals Private Limiited (IN) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219914-A1 | PROCESS FOR PREPARING PITOLISANT HYDROCHLORIDE AND SOLID-STATE FORMS THEREOF | PITHD1, MLN, TPP1 | IGF1R 2867/4885ALOX15 3558/4885SLC6A2 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.