Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858117 | 0.85 | MAPT (0.41) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2854456 | 0.84 | MEN1 (0.47) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2855610 | 0.83 | CNR1 (0.58) | RAB9AMAPTKMT2AKDM4ECNR1 | |
| SCHEMBL2859025 | 0.78 | NAMPT (0.44) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2856094 | 0.76 | MAPT (0.42) | RAB9AALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL2854032 | 0.74 | MAPT (0.43) | RAB9AALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL2858063 | 0.73 | MAPT (0.57) | RAB9AALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL2858119 | 0.73 | MAPT (0.43) | RAB9AALDH1A1MAPTKDM4ECNR1 | |
| SCHEMBL2848353 | 0.73 | SMN1; SMN2 (0.48) | RAB9AALDH1A1MAPTKDM4ECNR1 | |
| SCHEMBL2860433 | 0.72 | MAPT (0.48) | RAB9AALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |