Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854455 | 0.91 | KMT2A (0.50) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL2854614 | 0.84 | MAPT (0.49) | RIPK1MAPTALDH1A1PYGLKMT2A | |
| SCHEMBL2858009 | 0.84 | SMN1; SMN2 (0.43) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL2850439 | 0.82 | KMT2A (0.53) | NAMPTKMT2AMEN1MAPK1ABCB1 | |
| SCHEMBL2855318 | 0.79 | ROCK1 (0.43) | MAPTALDH1A1MAPK1CCR1NPC1 | |
| SCHEMBL2854441 | 0.78 | RAB9A (0.45) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL2853095 | 0.78 | ALDH1A1 (0.58) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL2858117 | 0.76 | MAPT (0.41) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL2856094 | 0.75 | MAPT (0.42) | MAPTALDH1A1CCR1NPC1RAB9A | |
| SCHEMBL2858063 | 0.75 | MAPT (0.57) | MAPTALDH1A1CCR1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |