Diphenylether

Diphenylether

SCHEMBL28544646

O=C(c1cc[c]cc1)c1ccccc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 0.61
ALDH1A1 P00352 1/20 0.54
AKR1C3 P42330 1/20 0.52
POLB P06746 1/20 0.51
PARP10 Q53GL7 1/20 0.48
PGR P06401 1/20 0.47
ELANE P08246 1/20 0.47
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LTA4H P09960 1/20 0.46
TSHR P16473 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
NPC1 O15118 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
STS P08842 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL27940139 0.88 SRD5A2 (0.76) SRD5A2ALDH1A1AKR1C3POLBPARP10
Benzophenone SCHEMBL27855516 0.88 SRD5A2 (0.76) SRD5A2ALDH1A1AKR1C3POLBPARP10
SCHEMBL144448 0.88 ALDH1A1 (0.70) SRD5A2ALDH1A1AKR1C3ELANEATM
SCHEMBL5158928 0.84 SRD5A2 (0.55) SRD5A2ALDH1A1POLBPARP10TSHR
SCHEMBL26759067 0.84 SRD5A2 (0.84) SRD5A2ALDH1A1AKR1C3POLBPARP10
SCHEMBL1069817 0.84 SRD5A2 (0.84) SRD5A2ALDH1A1AKR1C3POLBPARP10
SCHEMBL234249 0.84 SRD5A2 (0.84) SRD5A2ALDH1A1AKR1C3POLBPARP10
SCHEMBL22415445 0.84 SRD5A2 (0.84) SRD5A2ALDH1A1AKR1C3POLBPARP10
SCHEMBL1082112 0.81 SRD5A2 (0.88) SRD5A2ALDH1A1AKR1C3POLBPARP10
SCHEMBL9536469 0.81 SRD5A2 (0.88) SRD5A2ALDH1A1AKR1C3POLBPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473674-B High flow polyaryletherketone compositions 提克纳有限责任公司 2021-03-02 CN disclosed