SCHEMBL144448

SCHEMBL144448

O=C(c1cc[c]cc1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.70
SRD5A2 P31213 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
ATM Q13315 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
RAB9A P51151 3/20 0.50
MAPT P10636 2/20 0.50
LMNA P02545 1/20 0.50
MAPK13 O15264 1/20 0.50
MAPK12 P53778 1/20 0.50
MAPK11 Q15759 1/20 0.50
MAPK14 Q16539 1/20 0.50
NPC1 O15118 2/20 0.48
HPGD P15428 1/20 0.48
PBRM1 Q86U86 1/20 0.48
AKR1C3 P42330 1/20 0.48
CES2 O00748 2/20 0.48
CES1 P23141 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL28861539 0.90 ALDH1A1 (0.70) ALDH1A1SRD5A2L3MBTL1ATMTDP1
SCHEMBL1535886 0.89 ALDH1A1 (0.50) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Diphenylether SCHEMBL28544646 0.88 SRD5A2 (0.61) ALDH1A1SRD5A2L3MBTL1ATMTDP1
SCHEMBL28052286 0.87 RAB9A (0.59) ALDH1A1SRD5A2L3MBTL1ATMTDP1
SCHEMBL3760594 0.87 RAB9A (0.64) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL27839064 0.87 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL27444367 0.87 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL27350158 0.87 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL2678745 0.87 ALDH1A1 (0.93) ALDH1A1SRD5A2L3MBTL1ATMTDP1
Benzophenone SCHEMBL30537001 0.84 ALDH1A1 (1.00) ALDH1A1SRD5A2L3MBTL1ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3188 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344265-A Amide compound and preparation method and application thereof 河北大学 2024-07-16 CN claimed
CN-118063472-A Imidazo [3,4-d ] pyrimidine compound and synthetic method and application thereof 河北大学 2024-05-24 CN claimed
US-20240093039-A1 WOOD-PRESERVING TREATMENT SOLUTION AND METHOD FOR PRODUCING WOOD PROVIDED WITH WOOD PRESERVATIVE AGC Inc. (JP) 2024-03-21 US claimed
CN-117551023-A Preparation method and application of N-thio-phenyl phthalimide compound 太原理工大学 2024-02-13 CN claimed
CN-117447370-A Preparation method of aggregation-induced emission material tetraaryl divinyl sulfide 山西蓬勃健康科技有限公司 2024-01-26 CN claimed
EP-3759231-B1 BIOCOMPATIBILITY COATING FOR CONTINUOUS ANALYTE MEASUREMENT HOFFMANN LA ROCHE (CH) 2023-10-18 EP claimed
US-20230301303-A1 A STORAGE STABLE INSECTICIDAL COMPOSITION UPL LTD (IN) 2023-09-28 US claimed
US-11702571-B2 Adhesive sheet for temporary fixation and method of manufacturing semiconductor device using the same LG CHEM, LTD. (KR) 2023-07-18 US claimed
CN-116283534-A Multifunctional chiral eneyne ligand and preparation method and application thereof 中国石油化工股份有限公司 2023-06-23 CN claimed
CN-116239578-A Piperazine dione ring compound, synthesis method thereof and application thereof in preparation of antitumor drugs 中国海洋大学 2023-06-09 CN claimed
US-4140681-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1979-02-20 US claimed
US-4131673-A INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1978-12-26 US claimed
US-4130563-A POLYMER INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1978-12-19 US claimed
US-4128536-A ULTRAVIOLET LIGHT ABSORBERS GAF CORPORATION (US) 1978-12-05 US claimed
US-4125604-A PEPTIDES, ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-11-14 US claimed
US-4101653-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-07-18 US claimed
US-4097472-A INHIBITION AND SUPRESSION OF THROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-27 US claimed
US-4093712-A ANTITHROMBOGENIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-06 US claimed
US-4082749-A FROM CARBOXAMIDES AND ALKALI METAL HYPOCHLORITE, CATALYST BASF AKTIENGESELLSCHAFT (DT) 1978-04-04 US claimed
US-4066773-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US claimed