Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | TOP1 | P11387 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263808 | 0.91 | FAAH (0.58) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL3660737 | 0.91 | FAAH (0.58) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL3660734 | 0.91 | FAAH (0.58) | FAAHTERTPTPN1PPARGPPARD | |
| Ammonia Solution, Strong SCHEMBL8661313 | 0.90 | FAAH (0.56) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL3659122 | 0.88 | MGLL (0.61) | FAAHPPARGPPARDPPARAMAPT | |
| SCHEMBL3659126 | 0.88 | MGLL (0.61) | FAAHPPARGPPARDPPARAMAPT | |
| SCHEMBL3661232 | 0.87 | ALDH1A1 (0.61) | PPARGPPARDPPARAHSD17B10FABP4 | |
| SCHEMBL8349314 | 0.86 | FAAH (0.46) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL8349312 | 0.86 | FAAH (0.46) | FAAHTERTPTPN1PPARGPPARD | |
| SCHEMBL4685864 | 0.83 | FAAH (0.45) | FAAHTERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940425-A | HER2 mutation inhibitors | 阿雷生物药品公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-111527078-B | Pyridinecarbonyl derivatives and their therapeutic use as TRPC6 inhibitors | 勃林格殷格翰国际公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-112654625-A | Heterocyclic and heteroaryl compounds for the treatment of huntington's disease | PTC医疗公司 | 2021-04-13 | — | — | CN | disclosed |