SCHEMBL28544894

SCHEMBL28544894

O=CCCCCc1ncc(Cl)[nH]1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.30
EPAS1 Q99814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7767311 0.74 HRH3 (0.37)
SCHEMBL19292469 0.73 NPY5R (0.44)
SCHEMBL19292285 0.71 PADI1 (0.35)
SCHEMBL19292508 0.70 PDE10A (0.55)
SCHEMBL19292150 0.69 PDE10A (0.46)
SCHEMBL19291976 0.68 PDE10A (0.43)
SCHEMBL29956446 0.68 TBXAS1 (0.56) HIF1A
SCHEMBL19292007 0.68 SCN2A (0.45)
SCHEMBL7467770 0.67 HRH2 (0.42) HIF1A
SCHEMBL238669 0.67 TBXAS1 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109535176-B Quinolone imidazole compound and preparation method and application thereof 西南大学 2021-04-20 CN disclosed