SCHEMBL28544902

SCHEMBL28544902

CCCCCCC(CC)C1CNCCN1CC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.34
GNAI3 P08754 5/20 0.33
GNAO1 P09471 5/20 0.33
GNAI1 P63096 5/20 0.33
BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8488954 0.79 DPP4 (0.35) SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL2764648 0.74 DPP4 (0.36)
SCHEMBL21431284 0.72 BCHE (0.38) BCHE
SCHEMBL6225365 0.71 GNAI3 (0.35) SIGMAR1GNAI3GNAO1GNAI1BCHE
SCHEMBL511996 0.69 TDP1 (0.34)
SCHEMBL26522941 0.67 BCHE (0.43) GNAI3GNAO1GNAI1BCHE
SCHEMBL27613286 0.67 BCHE (0.43) GNAI3GNAO1GNAI1BCHE
Hydrochloric Acid SCHEMBL3182984 0.67 DPP4 (0.34)
Hydrochloric Acid SCHEMBL3182976 0.67 DPP4 (0.34)
SCHEMBL3631849 0.67 SIGMAR1 (0.40) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232587-B Disubstituted 1,2, 4-triazine compounds 田边三菱制药株式会社 2021-04-13 CN disclosed