Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545116 | 0.94 | LMNA (0.51) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28220781 | 0.88 | MAPT (0.50) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28549976 | 0.88 | MAPT (0.50) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28221376 | 0.88 | ALDH1A1 (0.60) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL31522244 | 0.84 | ALDH1A1 (0.44) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28551082 | 0.82 | ALDH1A1 (0.46) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28550459 | 0.81 | SMN1; SMN2 (0.55) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28545194 | 0.80 | MAPT (0.41) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28555029 | 0.79 | MAPT (0.42) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL28544698 | 0.79 | NPC1 (0.45) | ALDH1A1RAB9ASMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117528-B | 2, 5-substituent-1, 3, 4-oxadiazole sulfone derivative, preparation method and application thereof | 贵州大学 | 2021-04-30 | — | — | CN | claimed |
| CN-108117528-B | 2, 5-substituent-1, 3, 4-oxadiazole sulfone derivative, preparation method and application thereof | 贵州大学 | 2021-04-30 | — | — | CN | disclosed |
| CN-108191786-B | 2, 5-substituent-1, 3, 4-oxadiazole disulfone derivative, preparation method and application thereof | 贵州大学 | 2021-04-30 | — | — | CN | disclosed |