Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28220781 | 0.94 | MAPT (0.50) | SMN1; SMN2MAPTALDH1A1POLBPTK2 | |
| SCHEMBL28549976 | 0.94 | MAPT (0.50) | SMN1; SMN2MAPTALDH1A1POLBPTK2 | |
| SCHEMBL28221376 | 0.94 | ALDH1A1 (0.60) | SMN1; SMN2MAPTALDH1A1POLBPTK2 | |
| SCHEMBL28545116 | 0.87 | LMNA (0.51) | SMN1; SMN2MAPTALDH1A1HTTRAB9A | |
| SCHEMBL28550444 | 0.85 | KMT2A (0.42) | SMN1; SMN2MAPTALDH1A1POLBRAB9A | |
| SCHEMBL28549119 | 0.82 | MAPT (0.42) | SMN1; SMN2MAPTALDH1A1POLBHTT | |
| SCHEMBL28544906 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2MAPTALDH1A1POLBHTT | |
| SCHEMBL28912449 | 0.72 | POLB (0.45) | MAPTALDH1A1POLBHTTRAB9A | |
| SCHEMBL28226524 | 0.72 | POLB (0.45) | MAPTALDH1A1POLBHTTRAB9A | |
| SCHEMBL28551082 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117528-B | 2, 5-substituent-1, 3, 4-oxadiazole sulfone derivative, preparation method and application thereof | 贵州大学 | 2021-04-30 | — | — | CN | claimed |
| CN-108117528-B | 2, 5-substituent-1, 3, 4-oxadiazole sulfone derivative, preparation method and application thereof | 贵州大学 | 2021-04-30 | — | — | CN | disclosed |