Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104121 | 0.82 | SCN9A (0.40) | LMNAKDM4E | |
| SCHEMBL29104114 | 0.82 | KMT2A (0.44) | KMT2APOLBALDH1A1CCNT1CDK9 | |
| SCHEMBL29104125 | 0.82 | POLB (0.42) | LMNAKMT2AHSD17B10POLBALDH1A1 | |
| SCHEMBL29104136 | 0.82 | KDM4E (0.39) | KMT2AHSD17B10ALDH1A1USP2RAB9A | |
| SCHEMBL29104126 | 0.81 | KMT2A (0.39) | LMNAKMT2AHSD17B10POLBALDH1A1 | |
| SCHEMBL29104142 | 0.81 | DRD2 (0.51) | ALDH1A1EEDKDM4E | |
| SCHEMBL29104137 | 0.81 | SCN9A (0.39) | KMT2AALDH1A1KDM4E | |
| SCHEMBL7848407 | 0.81 | DRD2 (0.51) | ALDH1A1EEDKDM4E | |
| SCHEMBL29104115 | 0.81 | GSK3B (0.43) | KMT2AHSD17B10POLBCDK4CCND1 | |
| SCHEMBL28770990 | 0.81 | ESRRA (0.43) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114539266-A | Maleimidocarbazole compound and synthesis method thereof | 湘潭大学 | 2022-05-27 | — | — | CN | claimed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114539266-A | Maleimidocarbazole compound and synthesis method thereof | 湘潭大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-112592344-B | Indolo [2,3-b ] indole derivative and synthetic method thereof | 湘潭大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-112592344-A | Indolo [2,3-b ] indole derivative and synthetic method thereof | 湘潭大学 | 2021-04-02 | — | — | CN | disclosed |