Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104121 | 0.90 | SCN9A (0.40) | KDM4ESRCDRD2SLC6A4CNR1 | |
| SCHEMBL29104115 | 0.86 | GSK3B (0.43) | HSD17B10DRD2SLC6A4CNR1KMT2A | |
| SCHEMBL7848407 | 0.86 | DRD2 (0.51) | KDM4EDRD2SLC6A4ALDH1A1RORC | |
| SCHEMBL29104126 | 0.86 | KMT2A (0.39) | KDM4EUSP2HSD17B10DRD2SLC6A4 | |
| SCHEMBL29104149 | 0.84 | MTNR1A (0.43) | — | |
| SCHEMBL6637786 | 0.83 | SLC6A4 (0.50) | SLC6A4CNR1RORC | |
| SCHEMBL28544938 | 0.82 | LMNA (0.48) | KDM4EUSP2HSD17B10RAB9AALDH1A1 | |
| SCHEMBL15712564 | 0.79 | DRD2 (0.50) | DRD2SLC6A4RORCSCN5ASCN9A | |
| SCHEMBL29104137 | 0.78 | SCN9A (0.39) | KDM4EDRD2SLC6A4CNR1ALDH1A1 | |
| SCHEMBL29104142 | 0.78 | DRD2 (0.51) | KDM4EDRD2SLC6A4ALDH1A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | claimed |
| CN-117003738-A | Imidazole spiro compound and synthesis method thereof | 湘潭大学 | 2023-11-07 | — | — | CN | disclosed |