Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557478 | 0.83 | ALDH1A1 (0.59) | KMT2AMEN1TSHRKDM4ENPSR1 | |
| SCHEMBL4740271 | 0.81 | MEN1 (0.52) | KMT2AMEN1TNFTSHRKDM4E | |
| SCHEMBL15997829 | 0.77 | NOTUM (0.56) | KMT2AMEN1TNFTSHRKDM4E | |
| SCHEMBL21333196 | 0.76 | LMNA (0.59) | KMT2AMEN1TNFTSHRKDM4E | |
| SCHEMBL21333334 | 0.72 | ALDH1A1 (0.51) | KMT2AMEN1TNFTSHRKDM4E | |
| SCHEMBL7878712 | 0.71 | TSHR (0.58) | KMT2AMEN1TSHRKDM4EALDH1A1 | |
| SCHEMBL15987314 | 0.71 | TSHR (0.61) | KMT2AMEN1TSHRKDM4EALDH1A1 | |
| SCHEMBL8861035 | 0.70 | TSHR (0.55) | KMT2AMEN1TSHRKDM4EALDH1A1 | |
| SCHEMBL21333083 | 0.69 | ALDH1A1 (0.47) | KMT2AMEN1TNFTSHRKDM4E | |
| SCHEMBL11523468 | 0.68 | TSHR (0.47) | KMT2AMEN1TSHRKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112442036-A | Novel purinone and imidazotriazinone derivatives having anti-glioma activity | 南开大学 | 2021-03-05 | — | — | CN | disclosed |