Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549493 | 0.81 | DPP4 (0.45) | PDK1NPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL28549495 | 0.81 | DPP4 (0.45) | PDK1NPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL28549007 | 0.80 | LMNA (0.46) | SCN4AMAPTPOLBSCN5ASCN3A | |
| SCHEMBL28560728 | 0.80 | PDK1 (0.38) | PDK1NPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL23306633 | 0.80 | LMNA (0.46) | SCN4AMAPTPOLBSCN5ASCN3A | |
| SCHEMBL23306592 | 0.80 | PDK1 (0.38) | PDK1NPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL28565602 | 0.77 | PDK1 (0.36) | PDK1NPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL28565598 | 0.77 | PDK1 (0.36) | PDK1NPC1RAB9ASMN1; SMN2SCN4A | |
| SCHEMBL29145421 | 0.70 | SCN4A (0.48) | SCN4ASCN5ASCN3A | |
| SCHEMBL29145449 | 0.68 | DPP4 (0.41) | PDK1NPC1RAB9ASMN1; SMN2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574191-B | Isoxazole heterocyclic compound and application thereof | 南京圣和药业股份有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112574191-A | Isoxazole heterocyclic compound and application thereof | 南京圣和药业股份有限公司 | 2021-03-30 | — | — | CN | disclosed |