Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.70 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.69 |
| ▸ | ATM | Q13315 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | PDE5A | O76074 | 6/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CDC42 | P60953 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362296 | 0.92 | EGFR (0.81) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL28573013 | 0.89 | EGFR (0.61) | EGFRERBB2L3MBTL1ATMMEN1 | |
| SCHEMBL8171663 | 0.89 | MEN1 (0.83) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL9514571 | 0.89 | MEN1 (0.78) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL28547411 | 0.88 | MMP2 (0.56) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL11205361 | 0.87 | EGFR (0.74) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL11210797 | 0.87 | EGFR (0.74) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL15301347 | 0.86 | MEN1 (0.82) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL15301136 | 0.86 | KDM4E (0.88) | EGFRERBB2L3MBTL1ATMRAB9A | |
| SCHEMBL10654063 | 0.86 | MEN1 (0.91) | EGFRERBB2L3MBTL1ATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574110-B | Preparation and application of acyl-substituted pyrazoline sulfonium salt derivative | 同济大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-112574110-A | Preparation and application of acyl-substituted pyrazoline sulfonium salt derivative | 同济大学 | 2021-03-30 | — | — | CN | disclosed |