Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545492 | 0.75 | LMNA (0.40) | KDM4EALDH1A1NPSR1PLD1LMNA | |
| SCHEMBL28545852 | 0.74 | PLD1 (0.41) | KDM4EALDH1A1PLD1LMNAGRIN2D | |
| SCHEMBL21258588 | 0.74 | PLD1 (0.41) | KDM4EALDH1A1NPSR1PLD1LMNA | |
| SCHEMBL28545491 | 0.74 | SMN1; SMN2 (0.42) | KDM4EALDH1A1PLD1GRIN2DGRIN3B | |
| SCHEMBL28541771 | 0.74 | ALDH1A1 (0.39) | KDM4EALDH1A1NPSR1PLD1USP2 | |
| SCHEMBL28545020 | 0.71 | HTT (0.41) | KDM4EALDH1A1PLD1LMNAGRIN2D | |
| SCHEMBL30565007 | 0.65 | PLD1 (0.44) | KDM4EALDH1A1PLD1LMNAGRIN2D | |
| SCHEMBL2096767 | 0.65 | PLD1 (0.44) | KDM4EALDH1A1PLD1LMNAGRIN2D | |
| SCHEMBL1140766 | 0.65 | PLD1 (0.47) | KDM4EALDH1A1PLD1GRIN2DGRIN3B | |
| SCHEMBL5145918 | 0.64 | PLD1 (0.43) | KDM4EALDH1A1PLD1LMNAGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678854-B | Method for synthesizing pyrido [1,2-a ] indole-6 (1H) -ketone compound by manganese catalysis | 陕西师范大学 | 2021-04-09 | — | — | CN | disclosed |