Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28545491 | 0.80 | SMN1; SMN2 (0.42) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21258588 | 0.80 | PLD1 (0.41) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28545492 | 0.78 | LMNA (0.40) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28545020 | 0.76 | HTT (0.41) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28541771 | 0.76 | ALDH1A1 (0.39) | PLD1KDM4EALDH1A1RAB9ACYP3A4 | |
| SCHEMBL28545490 | 0.74 | KDM4E (0.40) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2096767 | 0.70 | PLD1 (0.44) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30565007 | 0.70 | PLD1 (0.44) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1140766 | 0.70 | PLD1 (0.47) | PLD1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5145918 | 0.69 | PLD1 (0.43) | PLD1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678854-B | Method for synthesizing pyrido [1,2-a ] indole-6 (1H) -ketone compound by manganese catalysis | 陕西师范大学 | 2021-04-09 | — | — | CN | disclosed |