Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.45 |
| ▸ | PPARA | Q07869 | 11/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855837 | 0.84 | ITGA4 (0.39) | PPARGPPARABRD4PAX8CREBBP | |
| SCHEMBL7446003 | 0.84 | KMT2A (0.41) | CYP2C9CYP2C19BRD4PAX8MEN1 | |
| SCHEMBL7308442 | 0.84 | KMT2A (0.41) | CYP2C9CYP2C19BRD4PAX8MEN1 | |
| SCHEMBL6139113 | 0.82 | MEN1 (0.40) | BRD4MEN1PLA2G1BHTTKMT2A | |
| SCHEMBL27597531 | 0.82 | MEN1 (0.40) | BRD4MEN1PLA2G1BHTTKMT2A | |
| SCHEMBL8380101 | 0.81 | KMT2A (0.45) | MEN1PLA2G1BHTTKMT2ANPSR1 | |
| SCHEMBL27597529 | 0.79 | MEN1 (0.42) | PPARGPPARAPPARDPAX8MEN1 | |
| SCHEMBL6139041 | 0.79 | MEN1 (0.42) | PPARGPPARAPPARDPAX8MEN1 | |
| SCHEMBL2861381 | 0.79 | XBP1 (0.37) | PAX8MEN1PLA2G1BHTTKMT2A | |
| SCHEMBL2855207 | 0.79 | ITGA4 (0.37) | BRD4PAX8CREBBPMEN1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346971-B1 | Production method for biarylalanine | SUMITOMO CHEMICAL CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |