Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 11/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855837 | 0.87 | ITGA4 (0.39) | ITGA4ITGB7NR1H4MEN1KMT2A | |
| SCHEMBL7308442 | 0.84 | KMT2A (0.41) | ITGA4ITGB7MEN1PLA2G1BHTT | |
| SCHEMBL7446003 | 0.84 | KMT2A (0.41) | ITGA4ITGB7MEN1PLA2G1BHTT | |
| SCHEMBL2861381 | 0.82 | XBP1 (0.37) | MEN1PLA2G1BHTTKMT2ANPSR1 | |
| SCHEMBL8909415 | 0.81 | KMT2A (0.40) | MEN1PLA2G1BHTTKMT2ANPSR1 | |
| SCHEMBL8380101 | 0.81 | KMT2A (0.45) | ITGA4ITGB7MEN1PLA2G1BHTT | |
| SCHEMBL2858258 | 0.81 | HDAC1 (0.42) | MEN1KMT2APAX8MAPTSMN1; SMN2 | |
| SCHEMBL2855171 | 0.80 | XDH (0.39) | MEN1PLA2G1BHTTKMT2ANPSR1 | |
| SCHEMBL7479568 | 0.79 | MT-CO2 (0.46) | MEN1PLA2G1BHTTKMT2ANPSR1 | |
| SCHEMBL7479440 | 0.79 | MT-CO2 (0.46) | MEN1PLA2G1BHTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346971-B1 | Production method for biarylalanine | SUMITOMO CHEMICAL CO (JP) | 2010-01-20 | — | — | EP | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |