Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446003 | 1.00 | KMT2A (0.41) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL8380101 | 0.92 | KMT2A (0.45) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL2861381 | 0.90 | XBP1 (0.37) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL1313198 | 0.88 | CYP1A2 (0.42) | PAX8PDCD1CD274CTSSCTSK | |
| SCHEMBL7447969 | 0.88 | CYP1A2 (0.42) | PAX8PDCD1CD274CTSSCTSK | |
| SCHEMBL2855171 | 0.87 | XDH (0.39) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL2855837 | 0.86 | ITGA4 (0.39) | KMT2AMEN1PAX8ITGA4ITGB7 | |
| SCHEMBL2855207 | 0.84 | ITGA4 (0.37) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL7479568 | 0.84 | MT-CO2 (0.46) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL8909415 | 0.84 | KMT2A (0.40) | KMT2AMEN1PLA2G1BHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |