Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847944 | 0.78 | SIGMAR1 (0.31) | SIGMAR1ADRA2BHTR2AKCNH2 | |
| SCHEMBL2856666 | 0.78 | — | — | |
| SCHEMBL2851944 | 0.77 | TSHR (0.37) | TSHRSIGMAR1TAAR1SLC18A2 | |
| SCHEMBL2849595 | 0.76 | — | — | |
| SCHEMBL4453279 | 0.73 | TAAR1 (0.35) | TSHRSIGMAR1TAAR1SLC18A2 | |
| SCHEMBL30096500 | 0.73 | TAAR1 (0.35) | TSHRSIGMAR1TAAR1SLC18A2 | |
| SCHEMBL2850046 | 0.73 | CYP3A4 (0.41) | — | |
| SCHEMBL2846403 | 0.73 | — | — | |
| SCHEMBL2852135 | 0.73 | — | — | |
| SCHEMBL14820737 | 0.68 | ALDH1A1 (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | claimed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | claimed |
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |