Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049808 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL12465779 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL2919461 | 0.77 | MAPT (0.52) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL2847944 | 0.76 | SIGMAR1 (0.31) | — | |
| SCHEMBL29822698 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL29406125 | 0.74 | MAPT (0.37) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL29444117 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL229536 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL238097 | 0.74 | MAPT (0.37) | ALDH1A1MAPTL3MBTL1NSD2EGFR | |
| SCHEMBL8615638 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPTL3MBTL1EGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758416-B1 | NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING (US) | 2018-05-09 | — | — | EP | disclosed |
| EP-2758413-B1 | IRIDIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING (US) | 2018-03-07 | — | — | EP | disclosed |
| US-9545624-B2 | Nickel containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2017-01-17 | — | — | US | disclosed |
| US-9480977-B2 | Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-11-01 | — | — | US | disclosed |
| US-9221041-B2 | Iridium containing hydrosilylation catalysts and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-20140275329-A1 | Ruthenium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW SILICONES CORPORATION | 2014-09-18 | — | — | US | disclosed |
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-09-04 | — | — | US | disclosed |
| US-20140231702-A1 | Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-08-21 | — | — | US | disclosed |
| US-20140206869-A1 | Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-24 | — | — | US | disclosed |
| US-20140194627-A1 | Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-07-10 | — | — | US | disclosed |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2014-07-03 | — | — | US | disclosed |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| WO-2013043783-A2 | COBALT CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043787-A2 | RUTHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043912-A2 | IRON CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043798-A2 | ZINC CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
| WO-2013043785-A2 | NICKEL CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206869-A1 | Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | ILK, ALG8, HIRA | ALDH1A1 1484/4885MAPT 2248/4885L3MBTL1 3049/4885 |
| US-20140231702-A1 | Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, CROCC, GYPA | ALDH1A1 2250/4885MAPT 2563/4885L3MBTL1 2807/4885 |
| US-20140183398-A1 | Nickel Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, ALG8, CAD | ALDH1A1 2299/4885MAPT 2757/4885L3MBTL1 3464/4885 |
| US-20140249311-A1 | Iron Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | TFRC, FTH1, HAMP | ALDH1A1 1738/4885MAPT 2816/4885L3MBTL1 2847/4885 |
| US-20140182483-A1 | Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | ITGA1, TMT1A, ITGA2 | ALDH1A1 2501/4885MAPT 2568/4885L3MBTL1 2422/4885 |
| US-20140194627-A1 | Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | ZRANB2, ZKSCAN2, SLC39A3 | ALDH1A1 1749/4885MAPT 2176/4885L3MBTL1 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.