SCHEMBL28545748

SCHEMBL28545748

CCc1ccccc1[PH](=O)OCCCC(C)C

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PPIA P62937 1/20 0.32
HPGD P15428 2/20 0.31
ATM Q13315 1/20 0.31
GPR88 Q9GZN0 1/20 0.31
HTT P42858 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28542296 0.91 HTT (0.35) MAPTL3MBTL1NPSR1HTTTDP1
SCHEMBL28554162 0.84 L3MBTL1 (0.39) MAPTL3MBTL1NPSR1HPGDATM
SCHEMBL28551818 0.83 P2RX7 (0.36) MAPTPPIAHPGDGPR88HTT
SCHEMBL28545745 0.83 TSHR (0.40) MAPTL3MBTL1NPSR1HPGDATM
SCHEMBL28546044 0.81 TSHR (0.41) MAPTADRA2AMEN1ALDH1A1KMT2A
SCHEMBL28541537 0.81 ALDH1A1 (0.36) MAPTL3MBTL1NPSR1HTTADRA2A
SCHEMBL28552223 0.80 L3MBTL1 (0.37) MAPTL3MBTL1NPSR1HPGDATM
SCHEMBL28269800 0.79 HTT (0.39) HPGDHTTTDP1ALDH1A1
SCHEMBL28547936 0.78 PPIA (0.36) PPIAHPGDGPR88HTTTDP1
SCHEMBL779740 0.77 MAPT (0.39) MAPTL3MBTL1NPSR1HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293805-B Olefin polymerization solid catalytic component, component preparation method and catalyst system thereof 中国石油天然气股份有限公司 2021-03-09 CN claimed
CN-109293805-B Olefin polymerization solid catalytic component, component preparation method and catalyst system thereof 中国石油天然气股份有限公司 2021-03-09 CN disclosed