Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17179811 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDABCB1XDH | |
| SCHEMBL17485808 | 0.87 | XDH (0.62) | ALDH1A1KDM4ECYP3A4ABCG2HPGD | |
| SCHEMBL6565198 | 0.87 | ALDH1A1 (0.60) | ALDH1A1KDM4ECYP3A4HPGDMAPK1 | |
| SCHEMBL16942322 | 0.86 | ALDH1A1 (0.76) | ALDH1A1ABCB1XDH | |
| SCHEMBL21588102 | 0.85 | ALDH1A1 (0.71) | ALDH1A1ABCB1XDH | |
| SCHEMBL23743756 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ABCB1XDH | |
| SCHEMBL29101712 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KDM4ECYP3A4ABCG2HPGD | |
| SCHEMBL29169330 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4ECYP3A4ABCG2HPGD | |
| SCHEMBL31190926 | 0.80 | CBS (0.67) | ALDH1A1KDM4ECYP3A4HPGDMAPK1 | |
| SCHEMBL28684198 | 0.80 | CBS (0.67) | ALDH1A1KDM4ECYP3A4HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925427-B | Application of rice OsT5H gene as negative regulatory factor in promoting rice thrombosis | 浙江大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-111925427-A | Application of rice OsT5H gene as negative regulatory factor in promoting rice thrombosis | 浙江大学 | 2020-11-13 | — | — | CN | disclosed |